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Menu reference › [Region Edit]▾
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[Region Edit] Menu

The [Region Edit] menu refines binary region masks in place through 3D morphological cleanup, slice-intensity filtering, connected-component tools, and multi-region Boolean or parcellation operations. Single-region edits modify the highlighted row by default and can be reverted with [Regions][Undo] (Ctrl+Shift+Z), while the Regions menu, Region Move menu, and ROI-Based Fiber Tracking cover file management, spatial shifts, and tracking roles.

Checked regions

Menu item Behavior
Modify All Checked Checkable toggle (off by default) that applies single-region edits to all checked regions instead of only the highlighted row. Separate still splits only the first checked region, and Region set operations always process all checked regions.

Dilation and erosion

Menu item Behavior
Dilation Shortcut: Ctrl+Shift+D. Expands the region mask outward by 1 voxel in 3D, thickening thin tracking barriers or bridging single-voxel boundary gaps.
Dilation By Voxel… Expands the region mask outward in 3D by a chosen radius (1–100 voxels, default 10). Distance is measured in voxels rather than mm, so physical expansion scales with the region’s voxel size.
Dilation By Threshold… Expands the region outward by 1 voxel only where boundary neighbors meet an intensity cutoff on the active slice (pre-filled with Otsu’s threshold). Positive values grow into brighter voxels; negative values grow into darker voxels.
Erosioin By Threshold… Shrinks the region inward by 1 voxel only along borders that meet an intensity cutoff on the active slice (pre-filled with Otsu’s threshold; positive for brighter voxels, negative for darker voxels). (Spelled Erosioin By Threshold... in the menu.)
Erosion Shortcut: Ctrl+Shift+E. Shrinks the region mask inward by 1 voxel in 3D. Thin 1–2 voxel sheets or small islands can vanish completely; use [Regions][Undo] if over-eroded.

Opening and closing

Menu item Behavior
Opening Shortcut: Ctrl+Shift+O. Removes thin exterior protrusions, narrow bridges, and stray boundary spurs while preserving the main mask shape without uniform shrinkage.
Closing Shortcut: Ctrl+Shift+C. Fills small internal holes, narrow gaps, and boundary clefts without uniformly expanding the outer mask surface.

Smoothing and mask structure

Menu item Behavior
Smoothing Shortcut: Ctrl+Shift+S. Smooths jagged, stair-stepped 3D boundaries on the region mask. Because Ctrl+Shift+S is shared with [Regions][Save Checked Regions to one 4D NIFTI…], click this menu item directly if the shortcut conflicts.
Defragment Shortcut: Ctrl+Shift+F. Keeps only the single largest connected 3D piece of the region and deletes all smaller disconnected islands. Avoid using on bilateral or multi-part masks unless smaller pieces should be discarded.
Separate Shortcut: Ctrl+Shift+P. Splits disconnected 3D pieces into up to 256 new checked regions (<Name>_1, <Name>_2, …) while leaving the original region intact. Even with Modify All Checked enabled, only the first checked region is split.
Negate Shortcut: Ctrl+Shift+N. Inverts the region mask across the full 3D volume, turning background voxels into foreground and vice versa. Intersect the result with a brain mask (via [Region Edit][All Intersect First]) to exclude outer background.

Threshold

Menu item Behavior
Threshold Shortcut: Ctrl+Shift+T. Filters existing voxels inside the region by active-slice intensity (pre-filled with Otsu’s threshold; positive values keep brighter voxels, negative values keep darker voxels). Never adds exterior voxels; use [Regions Misc][New Region From Thresholding…] for whole-slice thresholding.

Region set operations

All five operations require at least two checked regions and process them in top-to-bottom table order on the topmost checked region’s voxel grid (resampling any lower region on a different grid and clearing its undo history).

Menu item Behavior
All Intersect First Shortcut: Ctrl+Shift+1. Replaces each lower checked region in place with its overlap against the topmost checked region, leaving the topmost region unchanged. Requires at least 2 checked regions.
All Exclude First Shortcut: Ctrl+Shift+2. Subtracts the topmost checked region from each lower checked region in place, leaving the topmost region unchanged. Requires at least 2 checked regions.
First Excludes All Shortcut: Ctrl+Shift+3. Subtracts all lower checked regions from the topmost checked region in place (for example, to carve out ventricles or lesions), leaving lower regions unchanged. Requires at least 2 checked regions.
All Fit into First Shortcut: Ctrl+Shift+4. Clips, expands, and smooths all lower checked regions into a gap-free, non-overlapping parcellation filling the topmost checked region (lower rows take precedence where masks overlap; topmost stays unchanged). Requires at least 2 checked regions.
Refine All Shortcut: Ctrl+Shift+5. Adjusts shared borders across all checked regions (including the topmost) to follow local tissue intensities on the active slice, producing non-overlapping masks. Requires at least 2 checked regions and an active slice.